BDBM50584720 CHEMBL5088153
SMILES Cc1cc(NC(=O)Nc2cc(nn2-c2ccc(Cl)cc2)C(C)(C)C)ccc1Nc1ncnc2NC(=O)C(C)(C)Oc12
InChI Key InChIKey=DSZLKOXKYRREEO-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 20 hits for monomerid = 50584720
Affinity DataKi: 1nMAssay Description:Binding affinity to TrkB (unknown origin) assessed as inhibition constant by radiometric assayMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Sichuan University
Curated by ChEMBL
Sichuan University
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Binding affinity to TrkA (unknown origin) assessed as inhibition constant by radiometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Binding affinity to TrkC (unknown origin) assessed as inhibition constant by radiometric assayMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Sichuan University
Curated by ChEMBL
Sichuan University
Curated by ChEMBL
Affinity DataKi: 8nMAssay Description:Binding affinity to TrkA G595R mutant (unknown origin) assessed as inhibition constant by radiometric assayMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Sichuan University
Curated by ChEMBL
Sichuan University
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Binding affinity to TrkA G667C mutant (unknown origin) assessed as inhibition constant by radiometric assayMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Sichuan University
Curated by ChEMBL
Sichuan University
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of TrkA G595R mutant (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Sichuan University
Curated by ChEMBL
Sichuan University
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of TrkA G667C mutant (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
Sichuan University
Curated by ChEMBL
Sichuan University
Curated by ChEMBL
Affinity DataIC50: 126nMAssay Description:Inhibition of human DDR1 in presence of ATP by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 101nMAssay Description:Inhibition of human EphA8 in presence of ATP by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 269nMAssay Description:Inhibition of human FES in presence of ATP by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of human Mer in presence of ATP by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of human PTK5 in presence of ATP by radiometric assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor TYRO3(Homo sapiens (Human))
Sichuan University
Curated by ChEMBL
Sichuan University
Curated by ChEMBL
Affinity DataIC50: 138nMAssay Description:Inhibition of human RSE in presence of ATP by radiometric assayMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
Sichuan University
Curated by ChEMBL
Sichuan University
Curated by ChEMBL
Affinity DataIC50: 126nMAssay Description:Inhibition of human TAK1 in presence of ATP by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of TrkC (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of TrkB (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Sichuan University
Curated by ChEMBL
Sichuan University
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of TrkA (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Sichuan University
Curated by ChEMBL
Sichuan University
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of wild type TrkA (unknown origin) using poly(Glu: Tyr) as substrate preincubated for 15 mins followed by substrate addition and further i...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of wild type TrkB (unknown origin) using poly(Glu: Tyr) as substrate preincubated for 15 mins followed by substrate addition and further i...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of wild type TrkC (unknown origin) using poly(Glu: Tyr) as substrate preincubated for 15 mins followed by substrate addition and further i...More data for this Ligand-Target Pair