BDBM50584862 CHEMBL5087851

SMILES CN(C)C(=O)[C@H]1CSCc2c(cccc2C(=O)OC[C@@H](NC(=O)[C@@H]2CCCN2C(C)=O)C(=O)N1)-c1ccc(C(O)=O)c(c1)C(F)(F)F

InChI Key InChIKey=AIWVUCXHATYZQS-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50584862   

TargetKelch-like ECH-associated protein 1(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50584862(CHEMBL5087851)
Affinity DataKd:  37nMAssay Description:Binding affinity to Keap1 (unknown origin) at R415 assessed as dissociation constant by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetKelch-like ECH-associated protein 1(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50584862(CHEMBL5087851)
Affinity DataKd:  152nMAssay Description:Binding affinity to Keap1 (unknown origin) at R415 assessed as dissociation constant by surface plasmon resonance based direct binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed