BDBM50585047 CHEMBL5075335

SMILES CN1Cc2nn(C)cc2-c2cnc3[nH]cc(-c4cnn(CCCC1=O)c4)c3c2

InChI Key InChIKey=IMSFHJBONZQKCR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50585047   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50585047(CHEMBL5075335)
Affinity DataIC50: 13nMAssay Description:Inhibition of DYRK1A (unknown origin) at 1 uM by kinomescan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50585047(CHEMBL5075335)
Affinity DataIC50: 19nMAssay Description:Inhibition of DYRK1B (unknown origin) at 1 uM by kinomescan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50585047(CHEMBL5075335)
Affinity DataIC50: 70nMAssay Description:Inhibition of DYRK1B (unknown origin) measured after 6 hrs in presence of ATP by Z'-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50585047(CHEMBL5075335)
Affinity DataIC50: 158nMAssay Description:Inhibition of DYRK1A (unknown origin) measured after 6 hrs in presence of ATP by Z'-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed