BDBM50585049 CHEMBL5075321

SMILES CN1Cc2nn(C)c(C#N)c2-c2cnc3[nH]c(C)c(-c4cn(CCCC1=O)nc4C(F)(F)F)c3c2

InChI Key InChIKey=MNPDDWGYJIGNTR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50585049   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50585049(CHEMBL5075321)
Affinity DataIC50: 44nMAssay Description:Inhibition of DYRK1A (unknown origin) measured after 6 hrs in presence of ATP by Z'-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50585049(CHEMBL5075321)
Affinity DataIC50: 55nMAssay Description:Inhibition of DYRK1B (unknown origin) measured after 6 hrs in presence of ATP by Z'-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed