BDBM50586163 CHEMBL5094306

SMILES CCN1CCN(Cc2c(OC)cc(C)[nH]c2=O)C(=O)c2c(Cl)c(ccc12)-c1c(C)noc1C

InChI Key InChIKey=YENXFADXISFZBK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50586163   

TargetHistone-lysine N-methyltransferase EZH2(Human)
Tri-Institutional Therapeutics Discovery Institute

Curated by ChEMBL
LigandPNGBDBM50586163(CHEMBL5094306)
Affinity DataIC50: 489nMAssay Description:Inhibition of EZH2 (unknown origin) using 3H-SAM as substrate incubated for 1 hour by filter binding methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed