BDBM50586269 CHEMBL5083385

SMILES [H][C@]12CN(c3ccc4Nc5ncccc5C(C)N(C(=O)[C@H]5CC[C@@H](CC5)OC(C)C)c4c3)[C@]([H])(CO1)C2

InChI Key InChIKey=NSTOLUBLPHCKFS-UHFFFAOYSA-N

Data  1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50586269   

LigandPNGBDBM50586269(CHEMBL5083385)
Affinity DataIC50: 25nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) assessed as reduction in NADPH consumption using alpha-KG as substrate incubated for 60 mins by Kina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed