BDBM50587720 CHEMBL5195946

SMILES COc1ccc2C(=O)N(Cc3ccc(cc3)C(=O)NO)C(=O)c3cccc1c23

InChI Key InChIKey=DUDRNIOSRBCEFQ-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50587720   

TargetHistone deacetylase 6(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587720(CHEMBL5195946)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of full length human recombinant HDAC6 incubated for 30 to 60 mins by HDAC-Glo I/II assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587720(CHEMBL5195946)
Affinity DataIC50: 64nMAssay Description:Inhibition of full length human recombinant HDAC3 incubated for 30 to 60 mins by HDAC-Glo I/II assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587720(CHEMBL5195946)
Affinity DataIC50: 108nMAssay Description:Inhibition of full length human recombinant HDAC1 incubated for 30 to 60 mins by HDAC-Glo I/II assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587720(CHEMBL5195946)
Affinity DataIC50: 162nMAssay Description:Inhibition of full length human recombinant HDAC2 incubated for 30 to 60 mins by HDAC-Glo I/II assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetPolyamine deacetylase HDAC10(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587720(CHEMBL5195946)
Affinity DataIC50: 375nMAssay Description:Inhibition of full length human recombinant HDAC10 incubated for 30 to 60 mins by HDAC-Glo I/II assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587720(CHEMBL5195946)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of full length human recombinant HDAC8 incubated for 30 to 60 mins by HDAC-Glo I/II assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 11(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587720(CHEMBL5195946)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of full length human recombinant HDAC11 incubated for 30 to 60 mins by HDAC-Glo I/II assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed