BDBM50589328 CHEMBL5204317

SMILES CC(C)N1C[C@H](O)C[C@]11CCN(C2CCCCC2)C1=O

InChI Key InChIKey=RLWVOPCGEYKLQM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50589328   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Incyte Research Institute

Curated by ChEMBL
LigandPNGBDBM50589328(CHEMBL5204317)
Affinity DataIC50: 37nMAssay Description:Inhibition of 11beta-HSD1 in human PBMC cells using 3H-cortisone as substrate assessed as conversion of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Incyte Research Institute

Curated by ChEMBL
LigandPNGBDBM50589328(CHEMBL5204317)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of 11beta-HSD1 (unknown origin) using 3H-cortisone as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed