BDBM50589771 CHEMBL5208946

SMILES OC(=O)C(F)(F)F.O=C(NCc1ccco1)C1CN(CCN1)C(=O)c1cc(=O)[nH]c(=O)[nH]1

InChI Key InChIKey=BZOGAABBRAAQQF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50589771   

TargetProcathepsin L(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50589771(CHEMBL5208946)
Affinity DataIC50:  210nMAssay Description:Inhibition of human Cathepsin L using Z-Leu-Arg-AMC as fluorogenic substrate incubated for 60 mins by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50589771(CHEMBL5208946)
Affinity DataIC50:  8nMAssay Description:Inhibition of SARS-CoV-2 main protease using MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2 as fluorescent substrate preincubated for 10 mins followed by substrate ad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed