BDBM50589772 CHEMBL5082224

SMILES Clc1ccc(cc1Cl)N1CCN(CC1)C(=O)c1cc(=O)[nH]c(=O)[nH]1

InChI Key InChIKey=XREZIAMDGRLMGZ-UHFFFAOYSA-N

Data  4 IC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50589772   

TargetReplicase polyprotein 1ab(2019-nCoV)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50589772(CHEMBL5082224)
Affinity DataIC50:  5.10nMAssay Description:Inhibition of SARS-CoV-2 main protease using MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2 as fluorescent substrate preincubated for 10 mins followed by substrate ad...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(2019-nCoV)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50589772(CHEMBL5082224)
Affinity DataIC50:  680nMAssay Description:Inhibition of SARS-CoV-2 3CL protease by FRET assayMore data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(2019-nCoV)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50589772(CHEMBL5082224)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibition of SARS-CoV-2 main protease using MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2 as substrate preincubated for 30 mins followed by substrate addition and m...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(2019-nCoV)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50589772(CHEMBL5082224)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of SARS-CoV-2 main proteaseMore data for this Ligand-Target Pair