BDBM50590323 CHEMBL5173522

SMILES [O-][N+](=O)c1cc(ccc1Cl)S(=O)(=O)NC(=O)[C@@H]1Cc2cc(Br)c(OCc3ccc(cc3)-c3ccccc3)c(Br)c2CN1Cc1ccc(cc1)C#N

InChI Key InChIKey=QNYPSLHCWSPLIO-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50590323   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50590323(CHEMBL5173522)
Affinity DataKi:  0.350nMAssay Description:Binding affinity to Mcl-1 (unknown origin) assessed as inhibition constant using 5-FAM-QEDIIRNIARHLAQVGDSMDRSIPPG as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetApoptosis regulator Bcl-2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50590323(CHEMBL5173522)
Affinity DataKi:  0.450nMAssay Description:Binding affinity to Bcl-2 (unknown origin) assessed as inhibition constant using 5-FAM-QEDIIRNIARHLAQVGDSMDRSIPPG as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed