BDBM50590457 CHEMBL5193291

SMILES Cn1cc(-c2ccc(N(C(=O)NCc3ccccc3)C3CCC(Nc4ccc(C#N)cn4)CC3)cc2)ccc1=O

InChI Key InChIKey=HDJBGURZVALLMD-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50590457   

TargetCyclin-dependent kinase 13(Human)
West China Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590457BDBM50590457(CHEMBL5193291)
Affinity DataIC50: 10nMAssay Description:Irreversible inhibition of CDK13 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetCyclin-dependent kinase 13(Human)
West China Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590457BDBM50590457(CHEMBL5193291)
Affinity DataIC50: 10nMAssay Description:Inhibition of CDK13 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
West China Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590457BDBM50590457(CHEMBL5193291)
Affinity DataIC50: 52nMAssay Description:Inhibition of CDK12 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetCyclin-dependent kinase 7(Human)
West China Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590457BDBM50590457(CHEMBL5193291)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetCyclin-dependent kinase 8(Human)
West China Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590457BDBM50590457(CHEMBL5193291)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetCyclin-dependent kinase 9(Human)
West China Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590457BDBM50590457(CHEMBL5193291)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of CDK9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetCyclin-dependent kinase 2(Human)
West China Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590457BDBM50590457(CHEMBL5193291)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed