BDBM50590576 CHEMBL5190400

SMILES OC(=O)c1ccc(NC(=S)Nc2nc(cs2)-c2cccc(F)c2)cc1O

InChI Key InChIKey=XNSFUJDVVODLHY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50590576   

TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50590576(CHEMBL5190400 | US20250276953, Compound 1-14)
Affinity DataIC50: 1.83E+4nMAssay Description:Inhibition of human SIRT5 using fluorogenic substrate preincubated for 1 hr in presence of NAD followed by substrate addition and measured after 15 t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50590576(CHEMBL5190400 | US20250276953, Compound 1-14)
Affinity DataIC50: 1.83E+4nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent