BDBM50590589 CHEMBL5178183

SMILES CNS(=O)(=O)c1cccc(c1)-c1csc(NC(=S)Nc2ccc(C(O)=O)c(O)c2)n1

InChI Key InChIKey=IPELOICYMSBTLW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50590589   

TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50590589(CHEMBL5178183 | US20250276953, Compound 1-29)
Affinity DataIC50: 2.61E+4nMAssay Description:Inhibition of human SIRT5 using fluorogenic substrate preincubated for 1 hr in presence of NAD followed by substrate addition and measured after 15 t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50590589(CHEMBL5178183 | US20250276953, Compound 1-29)
Affinity DataIC50: 2.61E+4nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2025
Entry Details
US Patent