BDBM50590594 CHEMBL5193516

SMILES OC(=O)c1ccc(NC(=S)Nc2nc(cs2)-c2ccc(c(F)c2)[N+]([O-])=O)cc1O

InChI Key InChIKey=FTCHPFXJYNSVKO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50590594   

TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50590594(CHEMBL5193516 | US20250276953, Compound 1-35)
Affinity DataIC50: 1.49E+4nMAssay Description:Inhibition of human SIRT5 using fluorogenic substrate preincubated for 1 hr in presence of NAD followed by substrate addition and measured after 15 t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50590594(CHEMBL5193516 | US20250276953, Compound 1-35)
Affinity DataIC50: 1.49E+4nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2025
Entry Details
US Patent