BDBM50590597 CHEMBL5178975

SMILES OC(=O)c1ccc(NC(=S)Nc2nc(cs2)-c2ccc(F)c(c2)S(=O)(=O)NCc2ccccc2)cc1O

InChI Key InChIKey=LURGSWUQMLWAPX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50590597   

TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50590597(CHEMBL5178975 | US20250276953, Compound 1-38)
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of human SIRT5 using fluorogenic substrate preincubated for 1 hr in presence of NAD followed by substrate addition and measured after 15 t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50590597(CHEMBL5178975 | US20250276953, Compound 1-38)
Affinity DataIC50: 8.22E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2025
Entry Details
US Patent