BDBM50590696 CHEMBL5182740

SMILES ONC(=O)CCCCCOc1cccc(c1)-c1nnc(s1)-c1ccccc1

InChI Key InChIKey=MSYJFZKTFYNIJP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50590696   

TargetHistone deacetylase 1(Human)
Qilu University of Technology (Shandong Academy of Sciences)

Curated by ChEMBL
LigandPNGBDBM50590696(CHEMBL5182740)
Affinity DataIC50: 15nMAssay Description:Inhibition of HDAC1 in human HeLa cell nuclear extract using Boc-Lys(Ac)-AMC or Boc-Lys(triflouroacetyl)-AMC as substrate incubated for 30 mins and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Qilu University of Technology (Shandong Academy of Sciences)

Curated by ChEMBL
LigandPNGBDBM50590696(CHEMBL5182740)
Affinity DataIC50: 20nMAssay Description:Inhibition of HDAC6 in human HeLa cell nuclear extract using Boc-Lys(Ac)-AMC or Boc-Lys(triflouroacetyl)-AMC as substrate incubated for 30 mins and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Human)
Qilu University of Technology (Shandong Academy of Sciences)

Curated by ChEMBL
LigandPNGBDBM50590696(CHEMBL5182740)
Affinity DataIC50: 38nMAssay Description:Inhibition of HDAC1/HDAC2 in human HeLa cell nuclear extract using Boc-Lys(Ac)-AMC as substrate and measured by fluorometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Qilu University of Technology (Shandong Academy of Sciences)

Curated by ChEMBL
LigandPNGBDBM50590696(CHEMBL5182740)
Affinity DataIC50: 3.03E+3nMAssay Description:Inhibition of HDAC8 in human HeLa cell nuclear extract using Boc-Lys(Ac)-AMC or Boc-Lys(triflouroacetyl)-AMC as substrate incubated for 30 mins and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed