BDBM50590836 CHEMBL5170804

SMILES Cc1ccc(cc1)-c1c(CN2CCOCC2)nc2scc(C(=O)NN)n12

InChI Key InChIKey=MSIRVCGEZTUEOG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50590836   

TargetDihydrofolate reductase(Human)
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50590836(CHEMBL5170804)
Affinity DataIC50: 123nMAssay Description:Inhibition of recombinant human DHFR expressed in Escherichia coli incubated for 15 mins and measured by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50590836(CHEMBL5170804)
Affinity DataIC50: 246nMAssay Description:Inhibition of recombinant human EGFR incubated for 40 to 45 mins and measured after 15 mins by Kinase-Glo Max assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50590836(CHEMBL5170804)
Affinity DataIC50: 357nMAssay Description:Inhibition of recombinant human HER2 incubated for 40 to 45 mins and measured after 15 mins by Kinase-Glo Max assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed