BDBM50591019 CHEMBL5187337

SMILES Cn1cncc1C#CCN(C(=O)Cc1ccc(cc1C(F)(F)F)C(F)(F)F)c1ccccc1

InChI Key InChIKey=BWDIUCBHKQPJNL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50591019   

TargetDNA polymerase theta(Human)
Repare Therapeutics

Curated by ChEMBL
LigandPNGBDBM50591019(CHEMBL5187337)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of human DNA polymerase theta pol domain (1819 to 2590 residues) expressed in Escherichia coli BL21 (DE3) cells preincubated for 15 mins f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed