BDBM50591021 CHEMBL5174283

SMILES FC(F)(F)c1ccc(CC(=O)N(CC#Cc2cccnc2)c2ccccc2)c(c1)C(F)(F)F

InChI Key InChIKey=ONNGUAPSDHCJLI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50591021   

TargetDNA polymerase theta(Homo sapiens)
Repare Therapeutics

Curated by ChEMBL
LigandPNGBDBM50591021(CHEMBL5174283)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of human DNA polymerase theta pol domain (1819 to 2590 residues) expressed in Escherichia coli BL21 (DE3) cells preincubated for 15 mins f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed