BDBM50591055 CHEMBL5200952

SMILES COCCC(=O)N[C@@H]1CC[C@H](C1)Nc1ncc2c(Br)nn(-c3ccc4ncccc4c3)c2n1

InChI Key InChIKey=MOPGMSWMRUESSB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50591055   

TargeteIF-2-alpha kinase GCN2(Human)
Rapt Therapeutics

Curated by ChEMBL
LigandPNGBDBM50591055(CHEMBL5200952)
Affinity DataIC50: 74nMAssay Description:Inhibition of GCN2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargeteIF-2-alpha kinase GCN2(Human)
Rapt Therapeutics

Curated by ChEMBL
LigandPNGBDBM50591055(CHEMBL5200952)
Affinity DataIC50: 159nMAssay Description:Inhibition of GCN2 in human SK-OV-3 cells assessed as reduction in phosphorylation of eIF2alpha by cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed