BDBM50591101 CHEMBL5209373

SMILES Cc1c2[nH]c3ccc(OC(=O)c4ccccc4)cc3c2c(C)c2c1cc[nH]c2=O

InChI Key InChIKey=BPGBAEXPBQHBSV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50591101   

TargetLIM domain kinase 1(Human)
Universita Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50591101(CHEMBL5209373)
Affinity DataIC50: 50nMAssay Description:Inhibition of human recombinant LIMK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetLIM domain kinase 1(Human)
Universita Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50591101(CHEMBL5209373)
Affinity DataIC50: 50nMAssay Description:Inhibition of GST tagged recombinant LIMK1 (unknown origin) using cofilin as substrate by by SDS-PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetLIM domain kinase 1(Human)
Universita Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50591101(CHEMBL5209373)
Affinity DataIC50: 50nMAssay Description:Inhibition of LIMK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetLIM domain kinase 2(Human)
University of Orleans

Curated by ChEMBL
LigandPNGBDBM50591101(CHEMBL5209373)
Affinity DataIC50: 75nMAssay Description:Inhibition of LIMK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetLIM domain kinase 2(Human)
University of Orleans

Curated by ChEMBL
LigandPNGBDBM50591101(CHEMBL5209373)
Affinity DataIC50: 75nMAssay Description:Inhibition of human recombinant LIMK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetLIM domain kinase 2(Human)
University of Orleans

Curated by ChEMBL
LigandPNGBDBM50591101(CHEMBL5209373)
Affinity DataIC50: 75nMAssay Description:Inhibition of GST tagged recombinant LIMK2 (unknown origin) using cofilin as substrate by by SDS-PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed