BDBM50591527 CHEMBL5171972

SMILES CC(C)(C)CNC(=S)Nc1ccc2N(CCCCO)CCc2c1

InChI Key InChIKey=IROGSYKGEJSSQJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50591527   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University Federico Ii of Naples

Curated by ChEMBL
LigandPNGBDBM50591527(CHEMBL5171972)
Affinity DataIC50: 9.02E+3nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21(DE3) assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
University Federico Ii of Naples

Curated by ChEMBL
LigandPNGBDBM50591527(CHEMBL5171972)
Affinity DataIC50: 1.39E+4nMAssay Description:Inhibition of human recombinant sEH assessed as reduction in 6-methoxynaphthaldehyde formation using PHOME as substrate preincubated for 1 min follow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed