BDBM50591640 CHEMBL5192518

SMILES ONC(=O)c1ccc(\C=N\NC(=O)c2cc(nc(n2)-c2cccc(O)c2)N2CCOCC2)cc1

InChI Key InChIKey=QIXCKSONTDMMTH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50591640   

TargetHistone deacetylase 6(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50591640(CHEMBL5192518)
Affinity DataIC50: 15nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50591640(CHEMBL5192518)
Affinity DataIC50: 15nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50591640(CHEMBL5192518)
Affinity DataIC50: 15nMAssay Description:Inhibition of full-length HDAC6 (unknown origin) by Color-de-Lys assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
LigandPNGBDBM50591640(CHEMBL5192518)
Affinity DataIC50: 46nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM50591640(CHEMBL5192518)
Affinity DataIC50: 46nMAssay Description:Inhibition of PI3K-alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
LigandPNGBDBM50591640(CHEMBL5192518)
Affinity DataIC50: 46nMAssay Description:Inhibition of PI3Kalpha (unknown origin) expressed in baculovirus expression system using L-alpha-phosphatidylinositol as substrate by luminescence a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50591640(CHEMBL5192518)
Affinity DataIC50: 68nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM50591640(CHEMBL5192518)
Affinity DataIC50: 72nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM50591640(CHEMBL5192518)
Affinity DataIC50: 73nMAssay Description:Inhibition of PI3Kbeta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM50591640(CHEMBL5192518)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of PI3Kgamma (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50591640(CHEMBL5192518)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of HDAC4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 11(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50591640(CHEMBL5192518)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of HDAC11 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50591640(CHEMBL5192518)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed