BDBM50592184 CHEMBL5186952

SMILES CC(N)C1CN(C1)c1c(cncc1-c1cc(F)cc(Cl)c1)-c1nc2c(F)cc(F)cc2[nH]1

InChI Key InChIKey=JNNMLMQTWIYXOB-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50592184   

TargetSomatostatin receptor type 5(Human)
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50592184(CHEMBL5186952)
Affinity DataEC50:  0.316nMAssay Description:Agonist activity at human SST5 expressed in CHO-K1 cells assessed as reduction in NKH477-induced intracellular cAMP levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetSomatostatin receptor type 5(Human)
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50592184(CHEMBL5186952)
Affinity DataEC50:  0.320nMAssay Description:Agonist activity at human SST5 expressed in CHO-K1 cells assessed as reduction in NKH477-induced intracellular cAMP levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed