BDBM50592791 CHEMBL5199362

SMILES [H][C@]12CO[C@]3([H])N1[C@@]([H])(O[C@]3(C)c1ccc(NS(=O)(=O)c3ccccc3)cc1)[C@@](C)(O2)c1cccc(NS(=O)(=O)c2ccccc2)c1

InChI Key InChIKey=FWDSDDUBGGLTLG-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50592791   

TargetOrexin receptor type 2(Human)
University of Tsukuba

Curated by ChEMBL
LigandPNGBDBM50592791(CHEMBL5199362)
Affinity DataKi:  222nMAssay Description:Antagonist activity at human OX2R expressed in CHO-K1 cells assessed as inhibition of orexin-A-induced increase in calcium mobilization preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
University of Tsukuba

Curated by ChEMBL
LigandPNGBDBM50592791(CHEMBL5199362)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human OX1R expressed in CHO-K1 cells assessed as inhibition of orexin-A-induced increase in calcium mobilization preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed