BDBM50592808 CHEMBL5192110

SMILES COc1ccc(cc1)C(=O)Nc1cccc(c1)C1(C)OC2COC3N2C1OC3(C)c1cccc(NC(=O)c2ccc(OC)cc2)c1

InChI Key InChIKey=CEFZLJAZLPOVTE-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50592808   

TargetOrexin/Hypocretin receptor type 1(Human)
University of Tsukuba

Curated by ChEMBL
LigandPNGBDBM50592808(CHEMBL5192110)
Affinity DataKi:  11.7nMAssay Description:Antagonist activity at human OX1R expressed in CHO-K1 cells assessed as inhibition of orexin-A-induced increase in calcium mobilization preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
University of Tsukuba

Curated by ChEMBL
LigandPNGBDBM50592808(CHEMBL5192110)
Affinity DataKi:  12nMAssay Description:Antagonist activity at human OX1R expressed in CHO-K1 cells assessed as inhibition of orexin-A-induced increase in calcium mobilization preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetOrexin receptor type 2(Human)
University of Tsukuba

Curated by ChEMBL
LigandPNGBDBM50592808(CHEMBL5192110)
Affinity DataKi:  17nMAssay Description:Antagonist activity at human OX2R expressed in CHO-K1 cells assessed as inhibition of orexin-A-induced increase in calcium mobilization preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetOrexin receptor type 2(Human)
University of Tsukuba

Curated by ChEMBL
LigandPNGBDBM50592808(CHEMBL5192110)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human OX2R expressed in CHO-K1 cells assessed as inhibition of orexin-A-induced increase in calcium mobilization preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed