BDBM50593150 CHEMBL5205006

SMILES CC(C)N(CCN1CCN(CCC(=O)Nc2nc3c(C)cccc3s2)CC1)C(C)C

InChI Key InChIKey=RKANPVDHWNNOIX-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50593150   

TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Yeditepe University

Curated by ChEMBL
LigandPNGBDBM50593150(CHEMBL5205006)
Affinity DataKi:  121nMAssay Description:Displacement of [3H]DTG from sigma 2 receptor in rat liver membranes measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Yeditepe University

Curated by ChEMBL
LigandPNGBDBM50593150(CHEMBL5205006)
Affinity DataKi:  202nMAssay Description:Displacement of [3H]ifenprodil from recombinant human GluN2B NMDA receptor (unknown origin) expressed in dexamethasone-induced mouse L-M(TK-) cell af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Yeditepe University

Curated by ChEMBL
LigandPNGBDBM50593150(CHEMBL5205006)
Affinity DataKi:  809nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Yeditepe University

Curated by ChEMBL
LigandPNGBDBM50593150(CHEMBL5205006)
Affinity DataIC50:  240nMAssay Description:Inhibition of human recombinant AChe using acetylthiocholine iodide as substrate incubated for 10 mins by DTNB reagent based Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCholinesterase(Homo sapiens (Human))
Yeditepe University

Curated by ChEMBL
LigandPNGBDBM50593150(CHEMBL5205006)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of human recombinant BuChe using butyrylthiocholine iodide as substrate incubated for 10 mins by DTNB reagent based Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed