BDBM50593631 CHEMBL5174059

SMILES COc1cc(CN(c2ccc(F)c(C#Cc3cnc4[nH]nc(-c5ccc(F)cc5)c4c3)c2F)S(=O)(=O)c2cccnc2)c(cc1OC)[N+]([O-])=O

InChI Key InChIKey=BSBMWIPNLRRUIR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50593631   

TargetSerine/threonine-protein kinase B-raf(Human)
Shanghai Institute of Organic Chemistry

Curated by ChEMBL
LigandPNGBDBM50593631(CHEMBL5174059)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GST-tagged recombinant human B-RAF V600E mutant expressed in baculovirus expression system incubated for 1 hr in presence of ATP by FRE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed