BDBM50593670 CHEMBL5207305

SMILES CN(C)[C@@H]1CCCC[C@H]1N(C)c1ccc(c2nonc12)S(=O)(=O)NC(=O)Nc1c2CCCc2cc2CCCc12

InChI Key InChIKey=BBSZEVXDLBGRNJ-FGZHOGPDSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50593670   

TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50593670(CHEMBL5207305)
Affinity DataIC50:  636nMAssay Description:Inhibition of NLRP3 inflammasome activation in PMA differentiated LPS-primed human THP-1 cells assessed as reduction in nigericin-induced IL-1beta le...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed