BDBM50594132 CHEMBL5197386
SMILES [H][C@@]1(CC[C@@H](CC1)N(C)C)[C@@]1(C)Oc2c(O1)c(C)c(cc2Br)C(=O)NCc1c(C)cc(C)[nH]c1=O
InChI Key InChIKey=CHJLMVBYELJCLC-UYPAYLBCSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50594132
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital Of Guangdong Medical University
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of EZH2 (unknown origin)More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EZH1(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital Of Guangdong Medical University
Curated by ChEMBL
Affinity DataIC50: 0.470nMAssay Description:Inhibition of EZH1 (unknown origin)More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital Of Guangdong Medical University
Curated by ChEMBL
Affinity DataIC50: 7.40nMAssay Description:Inhibition of EZH2 (unknown origin) assessed as reduction in H3K27me3 levelMore data for this Ligand-Target Pair