BDBM50594247 CHEMBL5184823

SMILES NC(=O)c1ccc(Oc2ccc(cc2)C#N)cc1

InChI Key InChIKey=PQQFJYPJKKMNMX-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50594247   

TargetProtein mono-ADP-ribosyltransferase PARP10(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50594247(CHEMBL5184823)
Affinity DataIC50: 3.64E+3nMAssay Description:Inhibition of C-terminal his-tagged human PARP10 expressed in Escherichia coli Rosette2 (DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP15(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50594247(CHEMBL5184823)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of N-terminal his-tagged human PARP15 expressed in Escherichia coli Rosette2 (DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50594247(CHEMBL5184823)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of N-terminal his-tagged human PARP2 expressed in Escherichia coli Rosette2 (DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50594247(CHEMBL5184823)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of N-terminal his-tagged human PARP14 expressed in Escherichia coli Rosette2 (DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50594247(CHEMBL5184823)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of N-terminal his-tagged human TNKS1 expressed in Escherichia coli Rosette2 (DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50594247(CHEMBL5184823)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of N-terminal his-tagged human TNKS2 expressed in Escherichia coli Rosette2 (DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50594247(CHEMBL5184823)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of N-terminal his-tagged human PARP1 expressed in Escherichia coli Rosette2 (DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed