BDBM50594394 CHEMBL5195750

SMILES CC(N1CCN(Cc2ccc(cc2)C(=O)NO)CC1)c1ccccc1

InChI Key InChIKey=ZHVQXJZQHWNCES-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50594394   

TargetHistone deacetylase 6(Mouse)
Kansai University

Curated by ChEMBL
LigandPNGBDBM50594394(CHEMBL5195750)
Affinity DataIC50: 260nMAssay Description:Inhibition of mouse HDAC6 expressed in human HEK-293T cells using fluorescent peptide Ac-KGLGK(Ac)-MCA as substrate preincubated for 10 mins followed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Kansai University

Curated by ChEMBL
LigandPNGBDBM50594394(CHEMBL5195750)
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of human HDAC1 expressed in human HEK-293T cells using fluorescent peptide RHKKAc as substrate preincubated for 10 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
Kansai University

Curated by ChEMBL
LigandPNGBDBM50594394(CHEMBL5195750)
Affinity DataIC50: 1.23E+4nMAssay Description:Inhibition of human HDAC4 using fluorescent peptide Boc-Lys(trifluoroacetyl)-AMC as substrate preincubated for 10 mins followed by substrate addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Kansai University

Curated by ChEMBL
LigandPNGBDBM50594394(CHEMBL5195750)
Affinity DataIC50: 1.06E+5nMAssay Description:Inhibition of human ERG potassium channel by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed