BDBM50594400 CHEMBL5205202

SMILES ONC(=O)c1cccc(CN2CCN(CC2)C(c2ccccc2)c2ccccc2)c1

InChI Key InChIKey=AXOOZPHQPAOTFP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50594400   

TargetHistone deacetylase 6(Mouse)
Kansai University

Curated by ChEMBL
LigandPNGBDBM50594400(CHEMBL5205202)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of mouse HDAC6 expressed in human HEK-293T cells using fluorescent peptide Ac-KGLGK(Ac)-MCA as substrate preincubated for 10 mins followed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Kansai University

Curated by ChEMBL
LigandPNGBDBM50594400(CHEMBL5205202)
Affinity DataIC50: 4.66E+4nMAssay Description:Inhibition of human HDAC1 expressed in human HEK-293T cells using fluorescent peptide RHKKAc as substrate preincubated for 10 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
Kansai University

Curated by ChEMBL
LigandPNGBDBM50594400(CHEMBL5205202)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human HDAC4 using fluorescent peptide Boc-Lys(trifluoroacetyl)-AMC as substrate preincubated for 10 mins followed by substrate addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed