BDBM50594401 CHEMBL5192796

SMILES ONC(=O)c1ccc(CN2CCN(Cc3ccccc3)CC2)cc1

InChI Key InChIKey=YUDJFSRXZHYHCF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50594401   

TargetHistone deacetylase 6(Mouse)
Kansai University

Curated by ChEMBL
LigandPNGBDBM50594401(CHEMBL5192796)
Affinity DataIC50: 260nMAssay Description:Inhibition of mouse HDAC6 expressed in human HEK-293T cells using fluorescent peptide Ac-KGLGK(Ac)-MCA as substrate preincubated for 10 mins followed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
Kansai University

Curated by ChEMBL
LigandPNGBDBM50594401(CHEMBL5192796)
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of human HDAC4 using fluorescent peptide Boc-Lys(trifluoroacetyl)-AMC as substrate preincubated for 10 mins followed by substrate addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Kansai University

Curated by ChEMBL
LigandPNGBDBM50594401(CHEMBL5192796)
Affinity DataIC50: 1.04E+4nMAssay Description:Inhibition of human HDAC1 expressed in human HEK-293T cells using fluorescent peptide RHKKAc as substrate preincubated for 10 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Kansai University

Curated by ChEMBL
LigandPNGBDBM50594401(CHEMBL5192796)
Affinity DataIC50: 7.31E+4nMAssay Description:Inhibition of human ERG potassium channel by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed