BDBM50594445 CHEMBL5195838

SMILES Nc1ncnc2n(nc(-c3cn(CC(F)(F)c4ccccc4)nn3)c12)[C@@H]1CCCN(C1)C(=O)C=C

InChI Key InChIKey=DGJMHKMYSDYOFP-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50594445   

TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Weizmann Institute of Science

Curated by ChEMBL
LigandPNGBDBM50594445(CHEMBL5195838)
Affinity DataIC50: 4nMAssay Description:Inhibition of N-terminal 6XHis-tagged recombinant MKK7 (117 to 423 residues) (unknown origin) expressed in Escherichia coli BL21-DE3 preincubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Weizmann Institute of Science

Curated by ChEMBL
LigandPNGBDBM50594445(CHEMBL5195838)
Affinity DataEC50:  265nMAssay Description:Inhibition of N-terminal 6XHis-tagged recombinant MKK7 (117 to 423 residues) in human U2OS assessed as reduction in c-Jun phosphorylation level incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed