BDBM50594455 CHEMBL5200393

SMILES CCOC1CC1C(=O)Nc1cc2cc(N3CCN(CC3)C3(C)COCC3O)c(Cl)cc2cn1

InChI Key InChIKey=NUXNSYIMLJYFEN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50594455   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50594455(CHEMBL5200393)
Affinity DataIC50: 0.0832nMAssay Description:Inhibition of GST-tagged truncated human LRRK2 G2019S mutant using fluorescein-labeled LRRKtide as substrate preincubated for 15 mins followed by sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed