BDBM50594462 CHEMBL5194578

SMILES CC(n1c2cc(C(=O)NC3(C)CCS(=O)(=O)CC3)c(F)cc2n(-c2cc(OCC(F)F)ccc2F)c1=O)C(C)(C)O

InChI Key InChIKey=HOLPMTQENLFOTG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50594462   

TargetDiacylglycerol O-acyltransferase 2(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50594462(CHEMBL5194578)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human DGAT2 expressed in sf9 insect cell membrane assessed as reduction in 13C18-triolein product formation using 13C oleoyl-CoA as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed