BDBM50595096 CHEMBL5186678

SMILES CNC(=O)c1cccc(NC(=O)C(=C\c2ccc(o2)-c2ccc(cc2)C(O)=O)\C#N)c1

InChI Key InChIKey=MDNJWGXJRSZRCB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50595096   

TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50595096(CHEMBL5186678)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of human recombinant SIRT5 using Benzyl-Lys(succinyl)-AMC as substrate incubated for 2 hrs by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50595096(CHEMBL5186678)
Affinity DataIC50: 8.03E+3nMAssay Description:Inhibition of human recombinant SIRT5 using fluorogenic Benzyl-Lys(Succinyl)-AMC as substrate incubated for 2 hrs measured by fluoroscence based micr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed