BDBM50595710 CHEMBL5191938

SMILES Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@H](O)CN2C(=O)[C@@H](NC(=O)COCCOCCOCCOCCOCC(F)(F)c2cnc(nc2)-c2ccc(cc2)C(C(=O)NO)c2ccccc2F)C(C)(C)C)cc1

InChI Key InChIKey=HCYVFIZSHJPMGM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50595710   

TargetHistone deacetylase 4(Human)
Charles River Laboratories

Curated by ChEMBL
LigandPNGBDBM50595710(CHEMBL5191938)
Affinity DataIC50: 230nMAssay Description:Inhibition of recombinant HDAC4 (unknown origin) using Boc-Lys(TFA)-AMC as substrate by fluorescence based plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone deacetylase 1/2/3/8(Human)
Charles River Laboratories

Curated by ChEMBL
LigandPNGBDBM50595710(CHEMBL5191938)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of class 1 HDAC in human Jurkat E6.1 cells using Boc-Lys(Ac)-AMC as substrate incubated for 24 hrs by plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed