BDBM50595711 CHEMBL5172806

SMILES CCCN(CCCCOCCOCCOCC(=O)N[C@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C)C(C)(C)C)C[C@@H](C)NC(=O)c1ccc(cc1)-c1noc(n1)C(F)(F)F

InChI Key InChIKey=LNVXIMZTYRLPDR-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50595711   

TargetHistone deacetylase 4(Human)
Charles River Laboratories

Curated by ChEMBL
LigandPNGBDBM50595711(CHEMBL5172806)
Affinity DataIC50: 90nMAssay Description:Inhibition of recombinant HDAC4 (unknown origin) using Boc-Lys(TFA)-AMC as substrate by fluorescence based plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone deacetylase 9(Human)
Charles River Laboratories

Curated by ChEMBL
LigandPNGBDBM50595711(CHEMBL5172806)
Affinity DataIC50: 130nMAssay Description:Inhibition of recombinant HDAC9 (unknown origin) using Boc-Lys(TFA)-AMC as substrate by fluorescence based plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone deacetylase 5(Human)
Charles River Laboratories

Curated by ChEMBL
LigandPNGBDBM50595711(CHEMBL5172806)
Affinity DataIC50: 140nMAssay Description:Inhibition of recombinant HDAC5 (unknown origin) using Boc-Lys(TFA)-AMC as substrate by fluorescence based plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone deacetylase 7(Human)
Charles River Laboratories

Curated by ChEMBL
LigandPNGBDBM50595711(CHEMBL5172806)
Affinity DataIC50: 220nMAssay Description:Inhibition of recombinant HDAC7 (unknown origin) using Boc-Lys(TFA)-AMC as substrate by fluorescence based plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone deacetylase 1/2/3/8(Human)
Charles River Laboratories

Curated by ChEMBL
LigandPNGBDBM50595711(CHEMBL5172806)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of class 1 HDAC in human Jurkat E6.1 cells using Boc-Lys(Ac)-AMC as substrate incubated for 24 hrs by plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed