BDBM50595713 CHEMBL5208515

SMILES CCCN(CCCCOCCOCCOCCOCCOCC(=O)N[C@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C)C(C)(C)C)C[C@@H](C)NC(=O)c1ccc(cc1)-c1noc(n1)C(F)(F)F

InChI Key InChIKey=KBDZFZJFGKYVBZ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50595713   

TargetHistone deacetylase 4(Human)
Charles River Laboratories

Curated by ChEMBL
LigandPNGBDBM50595713(CHEMBL5208515)
Affinity DataIC50: 92nMAssay Description:Inhibition of recombinant HDAC4 (unknown origin) using Boc-Lys(TFA)-AMC as substrate by fluorescence based plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone deacetylase 9(Human)
Charles River Laboratories

Curated by ChEMBL
LigandPNGBDBM50595713(CHEMBL5208515)
Affinity DataIC50: 94nMAssay Description:Inhibition of recombinant HDAC9 (unknown origin) using Boc-Lys(TFA)-AMC as substrate by fluorescence based plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone deacetylase 5(Human)
Charles River Laboratories

Curated by ChEMBL
LigandPNGBDBM50595713(CHEMBL5208515)
Affinity DataIC50: 150nMAssay Description:Inhibition of recombinant HDAC5 (unknown origin) using Boc-Lys(TFA)-AMC as substrate by fluorescence based plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone deacetylase 7(Human)
Charles River Laboratories

Curated by ChEMBL
LigandPNGBDBM50595713(CHEMBL5208515)
Affinity DataIC50: 150nMAssay Description:Inhibition of recombinant HDAC7 (unknown origin) using Boc-Lys(TFA)-AMC as substrate by fluorescence based plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone deacetylase 1/2/3/8(Human)
Charles River Laboratories

Curated by ChEMBL
LigandPNGBDBM50595713(CHEMBL5208515)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of class 1 HDAC in human Jurkat E6.1 cells using Boc-Lys(Ac)-AMC as substrate incubated for 24 hrs by plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed