BDBM50595809 CHEMBL5175160

SMILES CNS(=O)(=O)c1ccc(Nc2ncc3c(n2)N([C@H]2CCC[C@@H]2C)C(=O)C32CC2)cc1

InChI Key InChIKey=HYCASJGOJJSHLV-GUYCJALGSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50595809   

TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50595809(CHEMBL5175160)
Affinity DataIC50:  230nMAssay Description:Inhibition of CDK2 in human COV318 cells incubated for overnight in presence of human whole blood by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50595809(CHEMBL5175160)
Affinity DataIC50:  0.330nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged full-length CDK2/Flag-tagged cyclinE1 expressed in baculovirus expression system using eIF4E-bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed