BDBM50595831 CHEMBL5190418

SMILES [2H]C([2H])([2H])NC(=O)c1nnc(NC(=O)C2CC2)cc1Nc1cccc(C(=O)Nc2ccc(C(=O)N3CCCC3)c(F)c2)c1OC

InChI Key InChIKey=DUJZUWWBMPOEDQ-FIBGUPNXSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50595831   

TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nanjing University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50595831(CHEMBL5190418)
Affinity DataIC50:  0.850nMAssay Description:Inhibition of TYK2 in human Jurkat cells assessed as reduction in IFNalpha induced STAT3 phosphorylation incubated for 24 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed