BDBM50595960 CHEMBL5192865

SMILES ONC(=O)c1ccc(CN(C2CC2)S(=O)(=O)c2cc(F)c(F)c(F)c2F)cc1

InChI Key InChIKey=HYEWQOQZANKATO-UHFFFAOYSA-N

Data  2 KI  22 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 24 hits for monomerid = 50595960   

TargetHistone deacetylase 6(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50595960(CHEMBL5192865)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of recombinant full length human HDAC6 expressed in insect Sf9 cells by EMSA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50595960(CHEMBL5192865)
Affinity DataIC50: 8.5nMAssay Description:Inhibition of full length human recombinant HDAC6 expressed in Sf9 baculovirus system using FAM-labeled acetylated peptide as substrate by measuring ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50595960(CHEMBL5192865)
Affinity DataKi:  17nMAssay Description:Inhibition of recombinant full length human HDAC6More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50595960(CHEMBL5192865)
Affinity DataKi:  17nMAssay Description:Binding affinity to full length human recombinant HDAC6 expressed in Sf9 baculovirus system assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50595960(CHEMBL5192865)
Affinity DataIC50: 334nMAssay Description:Inhibition of recombinant full length human HDAC8 expressed in insect Sf9 cells by EMSA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50595960(CHEMBL5192865)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of full length human recombinant HDAC1 expressed in Sf9 baculovirus system using FAM-labeled acetylated peptide as substrate by measuring ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50595960(CHEMBL5192865)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of full length human recombinant HDAC8 expressed in Sf9 baculovirus system using FAM-labeled acetylated peptide as substrate by measuring ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50595960(CHEMBL5192865)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of full length human recombinant HDAC3 expressed in Sf9 baculovirus system using FAM-labeled acetylated peptide as substrate by measuring ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50595960(CHEMBL5192865)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of full length human recombinant HDAC2 expressed in Sf9 baculovirus system using FAM-labeled acetylated peptide as substrate by measuring ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase 11(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50595960(CHEMBL5192865)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant full length HDAC11 (unknown origin) expressed in insect Sf9 cells by EMSA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50595960(CHEMBL5192865)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of full length human recombinant HDAC4 expressed in Sf9 baculovirus system using FAM-labeled acetylated peptide as substrate by measuring ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase 5(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50595960(CHEMBL5192865)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of full length human recombinant HDAC5 expressed in Sf9 baculovirus system using FAM-labeled acetylated peptide as substrate by measuring ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50595960(CHEMBL5192865)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant full length human HDAC2 expressed in insect Sf9 cells by EMSA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50595960(CHEMBL5192865)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant full length human HDAC1 expressed in insect Sf9 cells by EMSA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone deacetylase 7(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50595960(CHEMBL5192865)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of full length human recombinant HDAC7 expressed in Sf9 baculovirus system using FAM-labeled acetylated peptide as substrate by measuring ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50595960(CHEMBL5192865)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant full length human HDAC4 expressed in insect Sf9 cells by EMSA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone deacetylase 9(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50595960(CHEMBL5192865)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of full length human recombinant HDAC9 expressed in Sf9 baculovirus system using FAM-labeled acetylated peptide as substrate by measuring ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase 5(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50595960(CHEMBL5192865)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant full length human HDAC5 expressed in insect Sf9 cells by EMSA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50595960(CHEMBL5192865)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of full length human recombinant HDAC10 expressed in Sf9 baculovirus system using FAM-labeled acetylated peptide as substrate by measuring...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase 9(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50595960(CHEMBL5192865)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant full length human HDAC9 expressed in Sf9 cells by EMSA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone deacetylase 7(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50595960(CHEMBL5192865)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant full length human HDAC7 expressed in Sf9 cells by EMSA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50595960(CHEMBL5192865)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant full length human HDAC3 expressed in insect Sf9 cells by EMSA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone deacetylase 11(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50595960(CHEMBL5192865)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of full length human recombinant HDAC11 expressed in Sf9 baculovirus system using FAM-labeled acetylated peptide as substrate by measuring...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50595960(CHEMBL5192865)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant full length human HDAC10 expressed in Sf9 cells by EMSA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed