BDBM50596395 CHEMBL5196221

SMILES CC(=O)Nc1ccc(cc1)-n1cnc2cc(ccc12)-c1ccc(OCCN2CCCCC2)cc1

InChI Key InChIKey=GAXVYKWKQSGVIF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50596395   

TargetHigh affinity nerve growth factor receptor(Human)
Ain Shams University

Curated by ChEMBL
LigandPNGBDBM50596395(CHEMBL5196221)
Affinity DataIC50: 24nMAssay Description:Inhibition of recombinant His-tagged human TrKA expressed in baculovirus expression system by LanthaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Ain Shams University

Curated by ChEMBL
LigandPNGBDBM50596395(CHEMBL5196221)
Affinity DataIC50: 44nMAssay Description:Inhibition of recombinant His-tagged human FLT3 (564 to 958 residues) expressed in baculovirus expression system by LanthaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Ain Shams University

Curated by ChEMBL
LigandPNGBDBM50596395(CHEMBL5196221)
Affinity DataIC50: 93nMAssay Description:Inhibition of recombinant His-tagged human FLT3 D835Y mutant (564 to 958 residues) expressed in baculovirus expression system by LanthaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Ain Shams University

Curated by ChEMBL
LigandPNGBDBM50596395(CHEMBL5196221)
Affinity DataIC50: 97nMAssay Description:Inhibition of recombinant N-terminal GST/His6-tagged human FLT3 ITD mutant (571 to 993 residues) expressed in insect cells by LanthaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed