BDBM50596734 CHEMBL5181200::US20230348421, Compound 52

SMILES CC(C)CCc1ccc(CNC(=O)N(Cc2ccc(F)cn2)C2CCN(C)CC2)cc1

InChI Key InChIKey=CTIYKFZALMMSIV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50596734   

Target5-hydroxytryptamine receptor 2A(Human)
Geneora Pharma (Shijiazhuang) Co.

US Patent
LigandPNGBDBM50596734(CHEMBL5181200 | US20230348421, Compound 52)
Affinity DataIC50: 42.7nMAssay Description:NIH3T3-5HT2AR cells in the logarithmic growth phase were seeded into a white-wall clear-bottom 96-well plate at a density of 1000 cells per well, and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Geneora Pharma (Shijiazhuang) Co.

US Patent
LigandPNGBDBM50596734(CHEMBL5181200 | US20230348421, Compound 52)
Affinity DataIC50: 43nMAssay Description:Inverse agonist activity at 5-HT2A receptor (unknown origin) expressed in mouse NIH3T3 cells using o-nitrophenyl-D-galacto pyranoside incubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Geneora Pharma (Shijiazhuang) Co.

US Patent
LigandPNGBDBM50596734(CHEMBL5181200 | US20230348421, Compound 52)
Affinity DataIC50: 67nMAssay Description:Antagonist activity at 5-HT2A receptor (unknown origin) expressed in CHO-K1 cells assessed as reduction in intracellular Ca2+ mobilization incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed