BDBM50596740 CHEMBL5200155::US20230348421, Compound 99
SMILES CN1CCC(CC1)N(Cc1ccc(F)cn1)C(=O)NCc1ccc2OC(C)(C)C=Cc2c1
InChI Key InChIKey=RZEDKDVYRYOESM-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50596740
Affinity DataIC50: 17nMAssay Description:Antagonist activity at 5-HT2A receptor (unknown origin) expressed in CHO-K1 cells assessed as reduction in intracellular Ca2+ mobilization incubated ...More data for this Ligand-Target Pair
Affinity DataIC50: 17.3nMAssay Description:CHO-K1/5-HT2A cells in the logarithmic growth phase were seeded into a 384-well plate at a density of 10000 cells per well, and cultured in a 37° C.,...More data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Inverse agonist activity at 5-HT2A receptor (unknown origin) expressed in mouse NIH3T3 cells using o-nitrophenyl-D-galacto pyranoside incubated for 1...More data for this Ligand-Target Pair
Affinity DataIC50: 33.3nMAssay Description:NIH3T3-5HT2AR cells in the logarithmic growth phase were seeded into a white-wall clear-bottom 96-well plate at a density of 1000 cells per well, and...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Geneora Pharma (Shijiazhuang) Co.
US Patent
Geneora Pharma (Shijiazhuang) Co.
US Patent
Affinity DataIC50: 650nMAssay Description:CHO (Chinese Hamster Ovary) cells stably expressing hERG potassium channels were taken, and hERG potassium channel currents were recorded at room tem...More data for this Ligand-Target Pair