BDBM50596830 CHEMBL5179166

SMILES CCN1CCN(CC1)c1ccc(Nc2ncnc(n2)-c2cccnc2Nc2c(Cl)c(OC)cc(OC)c2Cl)cc1

InChI Key InChIKey=QVPHYLGGPUFPEQ-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50596830   

TargetFibroblast growth factor receptor 1(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50596830(CHEMBL5179166)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of wild-type FGFR1 (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetFibroblast growth factor receptor 2(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50596830(CHEMBL5179166)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of wild-type FGFR2 (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetFibroblast growth factor receptor 3(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50596830(CHEMBL5179166)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of FGFR3 K650E mutant (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetFibroblast growth factor receptor 2(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50596830(CHEMBL5179166)
Affinity DataIC50: 0.920nMAssay Description:Inhibition of FGFR2 N549H mutant (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetFibroblast growth factor receptor 3(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50596830(CHEMBL5179166)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of wild-type FGFR3 (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetFibroblast growth factor receptor 4(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50596830(CHEMBL5179166)
Affinity DataIC50: 11nMAssay Description:Inhibition of wild-type FGFR4 (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetFibroblast growth factor receptor 3(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50596830(CHEMBL5179166)
Affinity DataIC50: 42nMAssay Description:Inhibition of FGFR3 K650M mutant (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 1(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50596830(CHEMBL5179166)
Affinity DataIC50: 100nMAssay Description:Inhibition of IRAK1 (unknown origin) by biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase 16(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50596830(CHEMBL5179166)
Affinity DataIC50: 100nMAssay Description:Inhibition of MPSK1 (unknown origin) by biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetFibroblast growth factor receptor 3(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50596830(CHEMBL5179166)
Affinity DataIC50: 159nMAssay Description:Inhibition of FGFR3 V555M mutant (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetFibroblast growth factor receptor 1(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50596830(CHEMBL5179166)
Affinity DataIC50: 372nMAssay Description:Inhibition of FGFR1 V561M mutant (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed