BDBM50596842 CHEMBL5206623

SMILES COc1cc(OC)c(Cl)c(Nc2ncccc2-c2ncnc(Nc3ccc(nc3)N3CCOCC3)n2)c1Cl

InChI Key InChIKey=LFFMUTDOMVUDHX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50596842   

TargetFibroblast growth factor receptor 2(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50596842(CHEMBL5206623)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of FGFR2 N549H mutant (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetFibroblast growth factor receptor 3(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50596842(CHEMBL5206623)
Affinity DataIC50: 8.60nMAssay Description:Inhibition of wild-type FGFR3 (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetFibroblast growth factor receptor 3(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50596842(CHEMBL5206623)
Affinity DataIC50: 4.06E+3nMAssay Description:Inhibition of FGFR3 V555M mutant (unknown origin) by radiometric kinase activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed